Finding may advance creation of new drugs that target AMPA receptors to treat brain cancer, pain and Alzheimer’s disease By super cooling a molecule on the surface of brain cells down to about minus ...

In this study, researchers used positron emission tomography and a special tracer to study the relationship between the distribution of an important neuronal receptor (AMPA) and the occurrence and ...

While the COVID pandemic has thankfully been over for some time now, there is still a considerable number of people in the world (about 400 million) suffering from long COVID. Long COVID is a chronic ...

Neuroscientists from Johns Hopkins Medicine say they have determined how a brain cell surface molecule shapes the way certain neurons behave. The research, published October 2 in Nature, reveals how a ...

Glutamate-gated AMPA receptors mediate the fast component of excitatory signal transduction at chemical synapses throughout all regions of the mammalian brain. AMPA receptors are tetrameric assemblies ...

The research, published June 4 in Nature Structural & Molecular Biology, identifies critical connections between activity of the epilepsy drug perampanel and the resulting movements of the AMPA ...