Health care is undergoing an important and well-needed shift from a one-size-fits-all approach to more personalized, precise, patient-focused care. A similar approach needs to be implemented at scale ...
Our proposed Toxicity Adaptive Lists Design (TALE) is straightforward to implement, requiring the prespecification of a small number of parameters that define rules governing dose escalation, ...
17d
From FIH to POC -- Designing Phase I/Ib Trials with Efficiency, Upcoming Webinar Hosted by Xtalks
Attendees will gain insight into a flexible, integrated matrix model and global Phase I patient experience, supported by deep therapeutic expertise in complex indications such as endocrinology and ...
This is the Applied Clinical Trials Brief —your fast track to the latest insights shaping clinical operations and drug development.
Gastrointestinal-focused CRO Alimentiv is upgrading its clinical trials with software firm PhaseV’s adaptive trial technology. In a new collaboration, Alimentiv will combine PhaseV's machine learning ...
Real-world data (RWD) is transforming clinical research, augmenting existing randomized controlled trial (RCT) data to de-risk studies and improve generalizability. With regulators setting clearer ...
The integration of artificial intelligence (AI) and machine learning (ML) in oncology clinical trials is rapidly evolving alongside the broader field. For example, AI-driven adaptive trial designs may ...
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