Role of the RAAS in the Pathophysiology of Heart Failure ACE inhibitors have no effect on angiotensin II formed by alternate pathways. In contrast, ARBs would be expected to inhibit the biologic ...

Despite these discrepancies, the Heart Outcomes Prevention Evaluation (HOPE) trial provided compelling results in a somewhat similar study population. [40] The HOPE trial was designed to assess the ...

Atrial fibrillation, or AFib, is the most common heart rhythm disorder. With AFib, the beating of the upper chambers of your heart (the atria) becomes irregular, and blood has a harder time reaching ...

Vasodilatory shock is a life-threatening syndrome that requires immediate treatment; conventional vasopressors have a narrow therapeutic window and toxicities at high doses. New research findings are ...

Hypertension impairs blood vessels, neurons and white matter in the brain well before the condition causes a measurable rise in blood pressure, according to a new preclinical study from Weill Cornell ...