In the early and mid-1980s, scientists used phages to express recombinant proteins. The protein was retained inside the virions, so screening required growing viral plaques, creating a stamp of these ...

When a person receives a cancer diagnosis, treatment can often include chemotherapy. This method of treating cancer also can affect healthy cells. But what if there was a drug on the market that, ...

Chemists are taking a p[h]age from bacteria's playbook in order to beat viruses at their own game and develop new drugs to fight cancer and a host of other human diseases in the process. Chemists at ...

Mapping the individual amino acids where antibodies bind (epitopes) to target viral proteins (antigens) is crucial to predicting how target proteins may evolve to escape antibody binding, improve ...

The recently published recommendations of the European Commission Joint Research Centre (JRC) shine a spotlight on the versatility and scientific benefits of universal antibody libraries in ...

Reviewed by Michael Greenwood, M.Sc. In phage-display, a gene encoding the surface protein of a bacteriophage is replaced with a gene encoding a novel protein. The technique can be used in drug ...

Aims: Novel anticancer strategies have employed bacteriophages as drug carriers and display platforms for anticancer agents; however, bacteriophage-based platforms maintain their natural antibacterial ...

Collateral damage to normal microbiota, which can be associated with the use of less-specific chemical antibacterials, [4] is avoided. Nonetheless, there are several challenges that must be addressed ...