Mutations in the BRCA1 gene that are either inherited (germline) or acquired (somatic) might not be key to the initiation of prostate cancer, as previously thought, suggests the first study of its ...
Three decades after discoveries linking mutations in the BRCA1 gene to breast and ovarian cancer susceptibility, research led by Mays Cancer Center at The University of Texas Health Science Center at ...
AMPLITUDE is the first clinical trial to evaluate potential therapies for patients with mHSPC and known HRR gene alterations, with positive results supporting the niraparib-based combination regimen ...
In this study, researchers aimed to determine whether younger BRCA1/2 carriers who undergo oophorectomy can receive menopausal hormone therapy without increasing their risk of breast cancer.
Carriers of the BRCA1 cancer gene had a significantly increased risk of breast cancer if they used hormonal contraception (HC), pooled cohort data showed. Breast cancer risk increased by 29% in BRCA1 ...
When it was discovered by researchers in 1994, the BRCA1 gene was hailed as a landmark achievement not just in breast cancer prevention but in medicine in general. Its discovery led to the development ...
Scientists have found that breast cancer cells can trigger the self-destruction of the tumor-suppressing BRCA1 proteins. Of the more than 3 million people with breast cancer in the United Stated, ...
In women who have both breast cancer and the BRCA1 mutation, having surgery to remove the ovaries can significantly lower their risk of dying from the disease, suggests a new study published in the ...
The full name of the BRCA1 gene is “breast cancer 1, early onset,” and it codes for a tumor suppressor protein. Tumor suppressor proteins help repair DNA that has become damaged in order to ensure the ...
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