The discovery of Hoogsteen base pairs, an alternative pairing mode to the canonical Watson–Crick structure, has significantly broadened our understanding of DNA dynamics. This conformation, in which ...

In the double helix structure of DNA, thymine forms a base pair with adenine through two hydrogen bonds. This specific pairing is known as complementary base pairing and is essential for the stability ...

Scientists have precisely identified base pairs of the human genome that remained consistent over millions of years of mammalian evolution, and which play a crucial role in human disease. The team ...

Study Shows How Melting Point Analysis Infers the Presence of and Identifies SNPs The melting temperature (T m) of a PCR product is dependent on both the length and sequence of the DNA. Melting curve ...

Uduak Thomas, Senior Editor at GEN, took a minute away from the talks, posters, and expo hall to join Julianna LeMieux, PhD, GEN’s Deputy Editor in Chief, to talk about the meeting, the sessions they ...

DNA is the molecular basis of heredity, the inherited traits that pass between generations in a person's family tree. Embodied in the sequence of base pairs, DNA carries information between ...

Structural variations (SVs), including insertions, deletions, inversions, and substitutions, can profoundly influence gene regulation and phenotype.