In hepatocytes, bile acids are secreted into bile canaliculi by bile salt export pump (BSEP), cholesterol is secreted by ATP binding cassette subfamily G member 5 (ABCG5) and ABCG8 heterodimer and ...

Poisoning with paracetamol (acetaminophen—APAP) is a common cause of liver failure. However, not all the correlations that lead to liver damage from APAP are yet known. Especially the role of bile ...

New research links altered bile acids to chronic kidney disease progression, highlighting potential metabolic pathways ...

Scientists have discovered a new role for bile acids: they curb appetite by entering the brain. Their findings provide new insights into the signals and mechanisms by which satiety is controlled and ...

Pregnant Wistar rats (270–300 g) were housed individually and kept under conventional housing conditions with free access to food and water. Pups were born naturally on day 21–22 of gestation. On the ...

For the first time, a team of experts from the Technical University of Munich (TUM), RWTH Aachen University, and the German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE) has demonstrated the ...

Bile is a greenish-yellow liquid made and released by the liver and stored in the gallbladder. It aids in the digestion of food and fluids by breaking down fats into fatty acids. Your body then takes ...

You may experience bile acid malabsorption on its own or due to an underlying condition. Doctors typically treat it with medication and by suggesting dietary changes. Bile acid malabsorption (BAM) is ...

Bile acids that aid fat digestion are also found to reduce the rewarding properties of cocaine use, according to a new study. Bile acids that aid fat digestion are also found to reduce the rewarding ...

Reflux sometimes includes bile. Cutting out certain foods may help alleviate reflux, but consult with a doctor for the best ...

Please provide your email address to receive an email when new articles are posted on . Treatment with maralixibat led to greater reductions in least-squares mean change from baseline in morning ...