When you’re dragging yourself through the day, coffee can offer a reset. It can jolt your brain into action, sharpening your ...

For years, people from CEOs to novelists have taken tiny amounts of psychedelics to support well-being. New research shows that benefits for depression may be attributable to a placebo effect.

Depression continues to grip roughly 332 million people worldwide, according to World Health Organization estimates. While standard antidepressant medications offer relief for many, nearly half of ...

New research suggests that caffeine could help prevent stress-induced depression-like behaviors by influencing the gut-brain connection. In a study using mice, researchers found that administering ...

Perhaps the most intriguing implication of recent breakthrough research lies in an unexpected connection: the most rigorous mechanistic dissection of rapid antidepressant action identifies adenosine ...

The coffee paradox in adenosine-mediated antidepressant action. Depression (left) and coffee consumption (right) are both linked through adenosine signaling (center), creating a pharmacological ...