With the help of zinc reagents, chemists have found a loophole in rules that govern additions to chiral carbonyl compounds, a fundamental reaction in organic synthesis. The work, presented on March 24 ...

Reactions that form carbon-carbon bonds hold a place of special importance in chemical synthesis. Researchers who excel in this field develop a knack for applying these reactions masterfully and use ...

Products of unfavorable chemical equilibria are not readily observed because their high energy and increased reactivity result in low concentrations. Biological macromolecules use binding forces to ...

The proposed method for anti-Michael addition in this study can enable one-step synthesis of α-substituted carbonyl compounds, which are commonly used in pharmaceuticals. Their study was made ...

Students in introductory chemistry courses are taught that two of the most important reaction classes in organic chemistry are the addition of nucleophiles to carbonyl compounds and the addition of ...