Each cardiac muscle cell can have over 5,000 sarcomeres, which compounds both the shortening and relaxation events. "This process appears to be regulated by myosin-binding protein-C (cMyBP-C), which ...

The human heart, often described as the body's engine, is a remarkable organ that tirelessly beats to keep us alive. At the core of this vital organ, intricate processes occur when it contracts, where ...

This study investigates the role of a key interaction between Tropomyosin (Tpm) and Troponin T (TnT) in the regulation of cardiac muscle contraction, with a particular focus on understanding ...

Researchers at UT Southwestern Medical Center have identified a previously unrecognized small protein in cells of the human heart that plays a key role in heart muscle contraction. The protein is made ...

A team of researchers have discovered that a mutation in a ribosomal protein found specifically in heart and skeletal muscle leads to impaired cardiac contractility in mice. The mutation was found to ...