Signal transduction is the fundamental process by which cells convert external cues into tailored intracellular responses. Through a cascade of molecular events—beginning at the cell membrane with the ...
Protein tyrosine phosphatase non-receptor type 2 ( PTPN2 ) is a tyrosine phosphatase involved in T cell receptor signal ...
Blocking the PD-1 signal transduction by occupying the phosphorylated ITSM recognition site of SHP-2
In recent years, immune checkpoint therapy headed by programmed death receptor 1 (PD-1) and programmed death receptor-ligand 1 (PD-L1) has been proven to be safe and effective. However, clinical ...
DEATH DUEL: One TNF receptor 1 pathway activates apoptosis, another triggers gene expression-roles in seeming opposition, says David Goeddel. H. Hsu, H Shu, M. Pan, D.V. Goeddel, "TRADD-TRAF2 and ...
There's a whole lot going on in the nucleus of the cell. Genes are transcribed into complementary DNA and then translated to messenger RNA to carry instructions to the protein-building machinery, ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results
Feedback