Researchers at the Icahn School of Medicine at Mount Sinai have characterized how cellular senescence—a biological process in which aging cells change how they function—is associated with human brain ...

Mount Sinai and BPGbio scientists uncover novel molecular drivers from live brain samples that direct human brain structure and function from ...

Cellular senescence is a process in which the cell cycle becomes permanently arrested, thereby inhibiting cell division, proliferation and growth. Various cellular stresses, such as DNA damage, ...

Aging cells secrete substances known to promote the growth of cancer cells. The development of drugs that can selectively kill these cells or inhibit the secretion of substances is ongoing. The latest ...

This Collection supports and amplifies research related to SDG 3. This is a joint Collection across npj Aging, Nature Aging, Nature Metabolism, Nature Cell Biology and Scientific Reports. Please see ...

Explore the connection between neurodegeneration and cellular senescence in understanding brain structure and ageing.

Senescence, aging, and age-related diseases represent complex biological phenomena with significant impacts on human health, and metabolism and metabolomics play pivotal roles in understanding their ...

Aging is no longer viewed only as an inevitable slide toward frailty, but as a biological process that can be measured, ...

Findings from the Living Brain Project reveal how senescence processes involved in early brain development may also shape brain aging ...

Senescence, a phenomenon in which cells cease to divide and grow, can be caused by everything from natural DNA damage to treatment with chemotherapy. However, several mechanisms allow for cells to ...