Despite the immense amount of genetic material present in each cell, around 3 billion base pairs in humans, this material needs to be accurately divided in two and allocated in equal quantities. The ...

A research team at The University of Osaka has found a novel pathway for depositing CENP-A into vertebrate centromeres, which ...

The centromere of chromosomes plays a crucial role in cell division. Using the model plant Arabidopsis thaliana, an international team of researchers has investigated how two crucial proteins -- KNL2 ...

Advancements in genome sequencing have challenged the long-standing belief that the position of the centromere in the chromosome is fixed. Researchers from Okayama University, Japan, have analyzed ...

A genomic study of human and selected nonhuman primate centromeres has revealed their unimaginable diversity and speed of evolutionary change. Although centromeres are vital to proper cell replication ...

Two different types of centromeres evolved from a monocentromere, a macro-monocentromere in Cha. luteum and a holocentromere in Chi. japonica. Micrographs show mitotic chromosomes. The centromere is ...

This divergence illustrates rapid centromere evolution, even between closely related species. The researchers proposed a model in which active centromeres are maintained by CENH3-enriched CentM168 ...

Due to their repetitive and complex DNA sequences, centromeres have been viewed as the "black boxes" of the genome for decades. Often overlooked in sequencing projects but playing a critical role in ...