Join host Neil Lander as he welcomes Katy Rhynard, Associate Director of Laboratory Informatics at Gilead Sciences. In this episode, Katy discusses the intricacies of validating chromatographic ...

Discover how SciY is modernizing method transfer for pharma labs, and making the analyticla method transfer more digital.

The use of acidic MPAs (pH 2–4) is the default in pharmaceutical testing because they suppress silanol ionization (from Si-OH to Si-O -) and improve peak shape for basic drugs. However, highly ...

Nobel Laureate Linus Pauling, Ph.D., predicted in 1939 that hydrogen bonding would prove to be more significant in the field of biology than any other type of chemical bond. His prediction has been ...

Discover how the Pistoia Alliance is revolutionizing HPLC-UV method sharing with standardized, FAIR-aligned data formats ...

Chromatography is a process for separating components of a mixture for analysis. This is a component of our small molecule analysis testing and plays a critical part in identifying and quantifying ...

This field has evolved considerably through the integration of systematic design strategies, notably the incorporation of Analytical Quality by Design (AQbD) principles and robust statistical tools ...

Most adsorption chromatography methods are based on a direct chemical interaction of a solid-phase ligand with a complementary target site on some population of biomolecules. Examples include ...

A new method allows chemists to measure how fast a small molecule binds to and unbinds from a protein without modifying or labeling either molecule (Anal. Chem. 2014, DOI: 10.1021/ac503391c).

Antibodies are essential proteins produced by the immune system that recognize and bind to specific targets, known as antigens. Their high specificity and affinity make antibodies invaluable tools in ...