While off-label use may be permissible, contraindicated use still has a strong regulatory boundary as reinforced by FDA guidance finalized in 2025.

9 Akershus University Hospital, Department of Obstetrics and Gynecology, Lørenskog, Norway Objective To establish expert consensus on prescreening and contraindications to moderate-to-vigorous ...

The absolute contraindications for laparoscopic cholecystectomy from the 1980s (pregnancy, previous abdominal surgery, bowel obstruction, coagulopathy, obesity, cirrhosis, inability to tolerate ...

Haloperidol is a traditional or conventional antipsychotic used to treat schizophrenia, mania and other forms of psychosis. It is a derivative of butyrophenone and it acts by blocking the effects of ...

A new study has found that people with newly diagnosed OA (knee or hip) with contraindications to or precautions for NSAIDs use continue to be prescribed these drugs. Additionally they had higher use ...

Knee replacement surgery is performed in patients suffering from severe osteoarthritis or other arthritis that causes severe pain and limit mobility. Knee replacement surgery is performed to improve ...

Background Clinical guidelines recommend pregnant women without contraindication engage in regular physical activity. This is based on extensive evidence demonstrating the safety and benefits of ...

Many patients with atrial fibrillation are not taking oral anticoagulation because of an elevated bleeding risk, and this subset faces substantial risks of both ischemic and hemorrhagic stroke, a new ...

Birth Control Pills / Oral Contraceptive Pills are not recommended for women who have had blood clots or heart or kidney or liver problems and it increases the risk for certain cancers. The pill is ...