In a recent paper in ACS Central Science, researchers report a strategy for targeting covalent modifications to specific sites on proteins. The modifier molecules use an antibody to target a protein ...

The paradigm in nutritional science is shifting from studying isolated nutrients to understanding the complex food matrix.

Thousands of proteins are known to cause disease, but while the biological activity of these proteins is understood, the way to hit and modulate them with a drug is not. Nature still has ways to bind ...

The newly launched Hyku Biosciences provides a platform for covalent drug development which may be a better approach for treating diseases like cancer. One of Hsu's SuTEx molecules targets sites on ...

A research team has developed an innovative technique that enables precise modification of specific proteins within complex biological environments. A research team led by Professor Seung Soo Oh and ...

Covant Therapeutics, Roivant’s latest spin-off company, will have a major partner with whom to explore the benefits of covalency, courtesy of an exclusive research pact and licensing deal with ...

Proteins are important molecules—but they aren’t the only molecules in a cell, and they don’t operate alone. In a new preprint, the team behind the protein structure prediction software RoseTTAFold ...

Researchers at Baylor College of Medicine have developed an artificial intelligence (AI) model that reveals how protein modifications link genetic mutations to disease. The method, called DeepMVP and ...