August 3, 2010 — A single intravenous dose of the N-methyl-D-aspartate (NMDA) antagonist ketamine hydrochloride produces a robust antidepressant effect within 40 minutes in patients with ...
Jeffrey L. Jackson, M.D., M.P.H., from the Medical College of Wisconsin in Milwaukee, and colleagues estimated the prevalence of difficult patient encounters among adults seen in nonpsychiatric ...
For patients with major depression, there was a clinically meaningful but not statistically significant improvement in the primary endpoint with 20-mg azetukalner. There were significant improvements ...