The liver is a key insulin target tissue for the control of glucose metabolism. For example, the effect of insulin to inhibit hepatic glucose production (HGP) is essential for maintenance of normal ...
A protein that normally fosters tissue repair instead acts to inhibit healing when sugar levels are high. The role reversal helps explain why wounds heal slowly in people with diabetes. A protein that ...
These days, lymphomas, leukemias, and other kinds of cancers can be effectively treated using chimeric antigen receptor T cell (CAR T) therapies. Now, new research from scientists at Children’s ...
The human vascular system, a complex network of blood vessels, plays an essential role in maintaining health. Understanding the molecular mechanisms underlying vascular development is important for ...
Results suggest FOXO1 controls SOX2 and OCT4 expression. Scientists claim the forkhead box O (FOXO) transcription factor FOXO1 is an essential component of the cellular control mechanism that ...
The human vascular system, a complex network of blood vessels, plays an essential role in maintaining health. Understanding the molecular mechanisms underlying vascular development is important for ...
A recent study revealed that the FOXO1 gene may play an important role in the pathological mechanisms of Parkinson's disease. A recent study led by researchers at Boston University School of Medicine ...
Reactive oxygen species damage various cell components including DNA, proteins, and lipids, and these impairments could be a reason for severe human diseases including atherosclerosis. Forkhead box O1 ...
A University of South Florida (USF Health) preclinical study unexpectedly identified the gene Foxo1 as a potential treatment target for hereditary lymphedema. The research, published July 15 in The ...
The factors and steps controlling postinfection CD8⁺ T cell terminal effector versus memory differentiation are incompletely understood. Whereas we found that naive TCF7 (alias “Tcf-1”) expression is ...
ScienceDaily (June 29, 2012) — A recent study led by researchers at Boston University School of Medicine (BUSM) revealed that the FOXO1 gene may play an important role in the pathological mechanisms ...
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