A groundbreaking study has shed light on the critical role of a tRNA methylation enzyme, TRMT10A, in supporting brain function. The findings reveal how the absence of TRMT10A leads to a reduction in ...

Researchers say discoveries could expand the CRISPR toolbox and lead to more efficient, rapid diagnostic tools for detecting COVID-19, influenza, and RSV.

tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure. The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically ...

Researchers uncovered a previously unknown CRISPR immune response in bacteria that targets transfer RNAs. The newly ...

Across all domains of life, immune defenses foil invading viruses by making it impossible for the viruses to replicate. Most ...

A novel CRISPR defense mechanism, unlike known nucleases, specifically destroys transfer ribonucleic acids (tRNA) that are ...

Scientists have discovered a new CRISPR mechanism with precise activity, expanding the potential applications of the existing ...

IRE1α-driven production of 5’-tRH-Gly GCC during ER stress, aiding cellular adaptation in various eukaryotic organisms, ranging from yeast to humans To fill this knowledge gap, a group of researchers ...