From a marketing and adoption standpoint, humanizing AI agents can lower the barrier to first use. Karina Tymchenko, founder of digital marketing firm Brandualist, says vendors often see higher ...

Severely immunodeficient mice engrafted with functional human cells and tissues, known as 'humanized' mice, facilitate progress in studies of human haematopoiesis, immunity, gene therapy, infectious ...

As health systems worldwide enter a new year marked by rapid technological expansion, rising costs, and ageing populations, a ...

In vivo models of human immunity in human tumor-bearing mice are frequently used to study mechanisms of targeted immunotherapies, safety, and efficacy. In a recent webinar Jenny Rowe, PhD, Scientist ...

For the first time, scientists have successfully created a type of mouse with a 100% functional human immune system and human-like gut microbiome. This 'humanized' mouse takes the guesswork out of ...

Mice are commonly used as models of human disease, helping scientists to understand the workings of complex pathologies and develop safe and efficacious drugs. It is now possible to create a range of ...

Humanized immune system mice are revolutionary research tools for the development of novel immune cell-targeting oncology therapeutics, but the use of first-generation models such as the huNOG (NOG ...

A severe organ shortage plagues the progress of organ transplantation. One solution may be to generate human organs in other large mammals, however, that process is challenging. Now, researchers have ...

Why do 80 to 90% of people infected with COVID-19 experience only mild cases while 10 to 20% face more severe or life-threatening symptoms? Researchers in the lab of Yale’s Richard Flavell decided to ...

Ray Lambert looks at the potential of humanized FcRn mice for evaluating the pharmacokinetics of mAbs. Due to their extraordinary specificity and pharmacokinetic (PK) behavior, human immunoglobulin ...