The phase 2a trial showed GR-0621 met primary and secondary endpoints, demonstrating safety and efficacy over 12 weeks. Phase 2a data show oral GRI-0621 was safe and improved immune and fibrosis ...

Multiple Independent Molecular Signals Converge to Validate GRI-0621 as a Potential Disease-Modifying TherapyLA JOLLA, CA, (GLOBE ...

Our lungs are permanently exposed to harmful environmental factors that can damage or even destroy their cells. In a specific regenerative process these injured cells must be replaced as soon as ...

Postdoctoral fellow positions are open immediately in Dr. Liu's lab to study the role of cellular metabolism and inflammasome activation in the regulation of lung injury, repair and fibrosis. The ...

Researchers at Baylor College of Medicine and collaborating institutions have uncovered a key molecular player that is involved in lung repair and in the development of pulmonary fibrosis, a common ...

“In this study, we investigated the interplay between cigarette smoke, DNA damage and repair, focusing on the Nucleotide Excision Repair (NER) protein Xeroderma Pigmentosum Group C (XPC).” “In this ...

Humans can't live without lungs, but Ankit Bharat's patient did for 48 hours.

A UCLA-led research team has discovered a molecular switch that determines whether tiny blood vessels in premature infants’ lungs can regenerate after injury. A failure of this repair process is a ...

At the height of the SARS-CoV-2 pandemic, researchers in Thomas Marichal’s immunophysiology laboratory at the University of Liège were studying samples collected from the lungs of patients who had ...