The chicken major histocompatibility complex (MHC) represents a compact and evolutionarily distinct genomic region that plays a critical role in orchestrating adaptive immunity. Characterised by a ...
The result is one molecule that can be both a checkpoint degrader and a cancer vaccine ( Nature 2026, DOI: 10.1038/s41586-025 ...
Upon administration, VLPs are uptake by APC, like dendritic cells. VLPs can be presented by MHC-I or MHC-II, which are recognized by CD8+ and CD4+ T cells, respectively. For cellular response, CD8+ ...
The adaptive immune system is an antigen-specific structure that discriminates non-self molecules through the recognition of peptide antigens using receptor interactions between T-cells and ...
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