A new study reveals a critical vulnerability in a brain receptor targeted by a rare autoimmune disease. Researchers have ...

When it comes to brain proteins, small changes can make a dramatic difference. Researchers studying NMDA (N-methyl-D-aspartate) receptors, which are essential for learning, memory and moment-by-moment ...

Some serious brain disorders begin with symptoms that are easy to misinterpret. A person may become confused, forgetful or ...

New OHSU study maps antibody "hot spots" behind anti‑NMDAR encephalitis. Could change diagnosis and treatment.

Glutamate receptors, including AMPA and NMDA subtypes, are pivotal mediators of excitatory transmission and plasticity across the mammalian central nervous system. Their regulation, which involves ...

Researchers at Tel Aviv University have made a fundamental discovery: the NMDA receptor (NMDAR)—long studied primarily for its role in learning and memory—also plays a crucial role in stabilizing ...

The links between neurons are crucial to the brain, and brain cells can reorganize the way they are linked together in a phenomenon known as neuroplasticity. This process is ongoing during a lifetime, ...

Medically reviewed by Lindsay Cook, PharmD Key Takeaways Ketamine is used as an anesthetic in surgery for adults and children ...

Three distinct snapshots obtained with cryo-electron microscopy illustrate the arrangement of two of the four symmetrical subunits that make a functional NMDA receptor. During activation, as the ...