Immun’Âge® Granted Japanese Patent Recognizing Activation of Nrf2, the Body’s Master Cellular Defense Pathway

Backed by more than 30 peer-reviewed human clinical studies supporting endogenous antioxidant activity, cellular ...

CorriXR Therapeutics Announces Publication of Additional Preclinical Data Corroborating Ability of NRF2 Knockout to Restore Chemosensitivity in Solid Tumors

A new publication from CorriXR Therapeutics, an oncology focused biotherapeutics company developing genetic medicines to overcome drug resistance in solid tumors, shows that its novel CRISPR-directed ...
Science Daily

CRISPR unlocks a new way to defeat resistant lung cancer

Scientists used CRISPR to disable the NRF2 gene, restoring chemotherapy sensitivity in lung cancer cells and slowing tumor growth. The technique worked even when only a fraction of tumor cells were ...
JSTOR Daily

Mild heat shock at 40 °C increases levels of autophagy: Role of Nrf2

The exposure to low doses of stress induces an adaptive survival response that involves the upregulation of cellular defense systems such as heat shock proteins (Hsps), anti-apoptosis proteins, and ...
BioWorld

Shanghai Institute of Organic Chemistry discovers new KEAP1/NRF2/ARE pathway activators

Shanghai Institute of Organic Chemistry has described oleanamide derivatives acting as Kelch-like ECH-associated protein 1 (KEAP1)/nuclear factor erythroid 2-related factor 2 (NFE2-related factor 2; ...