The modulation of colorectal cancer (CRC) by oestrogen receptors has emerged as a field of great promise, drawing attention to the differential roles of receptor subtypes in tumour initiation, ...

New data links the liver receptor GPR110 to sex-specific progression of metabolic dysfunction-associated steatohepatitis.

Chronic kidney disease (CKD) affects more than 10% of the global population and is expected to become the fifth leading cause of death worldwide within the next two decades. Perhaps surprisingly, ...

A study led by researchers at the Hospital del Mar Research Institute advances one of the most significant milestones in breast cancer treatment, making immunotherapy effective against the most common ...

New review reveals how non-genomic estrogen signaling undermines treatment response and fuels tumor progression Hormone receptor–positive breast ...

Researchers confirm and explore the role of estrogen-related receptors in regulating energy production in muscle cells during exercise. The findings indicate that developing a drug to boost ...

Researchers discover that estrogen can turn on pain signals associated with conditions like irritable bowel syndrome. Women are dramatically more likely than men to suffer from irritable bowel ...

Estrogen-dependent cancers are cancers that grow in response to the hormone estrogen. These include certain types of breast cancer, uterine cancer, and ovarian cancer. In these cancers, estrogen can ...

A mouse study suggests estrogen may increase gut pain by activating specific cells, offering hints to why IBS is more common ...