Neuropeptide FF (NPFF) is an endogenous peptide that plays a critical role in modulating opioid receptor function. Its dual capacity to influence both opioid-induced analgesia and tolerance has ...

Muse Treatment Alcohol & Drug Rehab Los Angeles has published a new educational resource that explains how opioid receptors ...

Two different versions of the mu-opioid receptor within a cellular membrane illustrate how the receptor changes its conformation to send a signal into the cell. Scientists captured six high-resolution ...

University of Florida scientists have helped identify a novel drug compound that selectively activates pain-altering receptors in the body, offering a potentially safer alternative to conventional ...

Dornsife researchers created 3D models of opioids hitting brain receptors, and of naloxone stopping the receptors from activating. (Henry Kofman / Daily Trojan file photo) The opioid crisis has killed ...

Substances that activate adrenaline receptors as opposed to opioid receptors have similar pain-relieving properties to opioids minus the negative side effects. The corresponding study was published in ...

Opioid medications offer people relief from debilitating pain, but these drugs come with dangers: the risk for addiction, miserable withdrawal symptoms and the potential for fatal overdose. In a study ...

Pomrenze and colleagues performed detailed experiments which revealed that during opioid withdrawal, a neuropeptide molecule called dynorphin is released in the nucleus accumbens, where it activates ...

Drug discovery is shifting from static snapshots to moving pictures. Instead of inferring how medicines work from end results ...