A new study suggests that Cytochromes P450 (CYP450s) enzymes can sense and respond to stimuli, acting like soft robots in living systems. Study reveals an important discovery in the realm of ...
Study reveals an important discovery in the realm of nanomachines within living systems. Prof. Sason Shaik from the Hebrew University of Jerusalem and Dr. Kshatresh Dutta Dubey from Shiv Nadar ...
The first-ever structure of a full-length P450 enzyme has been solved. Cells use these enzymes to synthesize hormones and metabolize drugs. Chemists would like to engineer them to carry out reactions ...
M. Ekroos and T. Sjögren, "Structural basis for ligand promiscuity in cytochrome P450 3A4," Proc Natl Acad Sci, 103:13682-7, 2006. (Cited in 78 papers) Researchers at AstraZeneca in MöIndal, Sweden, ...
Structure of a twisting BINOL radical shown with a P450 enzyme in the background. A BINOL radical twists within a P450 enzyme. Credit: S. Luke Schulert Students of stereochemistry know that chirality ...
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