Researchers have identified two new breast cancer genes that also cause Lynch syndrome. Researchers at Columbia University Irving Medical Center and NewYork-Presbyterian have identified two new breast ...
Night shift work duration and risk of colorectal cancer according to IRS1 and IRS2 expression. Association between density of tumor infiltrating lymphocytes and disease-free survival (DFS) in patients ...
Clinical performance of a multimodal screening blood test for advanced adenomas and CRC in an average-risk cohort of 1,038 participants. This is an ASCO Meeting Abstract from the 2023 ASCO ...
New isoindolines acting as mismatch repair endonuclease PMS2 inhibitors have been reported in a Neophore Ltd. patent as useful for the treatment of cancer.
Researchers from Neophore Ltd. presented the discovery and preclinical evaluation of NP-1867, a small molecule inhibitor of DNA mismatch repair (MMR) protein PMS2, being developed for the treatment of ...