Researchers have discovered a new mechanism for potassium channel inhibitor entry, which could improve the specificity of drugs targeting the channel. Upon binding to calcium ions, BK channels allow ...

Ion channels in the nervous system are among the most important targets for insecticides. Understanding the structure of the channels is key for the identification of novel species-specific binding ...

Potassium channels are openings that allow charged potassium atoms to cross the cell membrane. Voltage-gated potassium channels—which open only when a specific voltage is reached across the cell ...

Intrigued by the properties of ion channel proteins commonly observed in cells, researchers have developed the first synthetic mechanosensitive potassium channel using a newly developed aromatic ...

Following this design principle, the researchers create angstrom-scale pores in bi-layer graphene sheets, and decorate the two pore edges with twisted rings of carbonyl groups. The artificial ion ...

Ion selectivity is an important property of cell membrane ion channels. For example, potassium ion channels are more permeable to potassium ions than to sodium ions. The mechanism underlying the ready ...