Using ribosome engineering (RE), researchers from Shinshu University introduced mutations affecting the protein synthesis ...
Scientists at the Institute of Molecular Biology and Biotechnology (IMBB-FORTH) and the University of Crete, together with ...
Research by UC Santa Cruz molecular biologist Harry Noller and his collaborators has led to the first direct observations of the mechanism for protein synthesis in living cells. Their new findings on ...
Before a newly synthesized protein can undergo folding, it must be processed and transported to the correct location within the cell after emerging from the ribosome. N-terminal acetylation ...
Researchers at VIB and KU Leuven have identified a molecular process that allows motor neurons to maintain protein production ...
Scientists from Uppsala University have used cryo-electron microscopy to reveal details of the protein synthesis mechanism in the parasite Giardia intestinalis, which causes diarrhoeal disease. The ...
A newly developed luciferase-based reporter can detect problems in protein translocation and disulfide bond formation in the endoplasmic reticulum (ER). Inspired by natural mechanisms found in ...
In a surprising discovery, University of New Mexico researchers have found that OTULIN – an enzyme that helps regulate the immune system – also drives ...
The FDA approval of denileukin diftitox (Lymphir) marked a significant shift in this paradigm. As a first-in-class immunotoxin, it employs a dual-action mechanism: directly targeting interleukin-2 (IL ...