Cells that are about to die send a signal to an executioner protein, but sometimes, those cells can fight back and regenerate ...

Individual mammalian cells contain billions of protein molecules, which must be synthesized, deployed, and removed with ...

To stay healthy, our cells rely on a self-cleaning mechanism that removes defective or unnecessary components. This process, ...

Proteins that are no longer needed, defective, or potentially harmful are labeled with a molecular "tag" and dismantled in ...

A new paper published today in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key ...

A selective protein degradation system known as Golgi membrane-associated degradation (GOMED), which identifies and removes ...

A protein essential to the human body for managing energy and regulating appetite relies on a partner protein, according to new research, and the findings could help researchers better understand ...

This review synthesizes clinical, genetic, and mechanistic evidence showing that suPAR and related uPAR fragments are ...

Silent cells deep in your spinal cord may hold a surprising key to healing after devastating injuries and brain disease. A ...

The startup is developing a medicine that can very specifically degrade cancerous forms of EGFR, the target of an array of ...