American teenagers are increasingly using a psychoactive substance called delta-8, sparking concerns the compound could pose a serious public health risk, a nation-wide study has found. Delta-8 THC, ...

Does using alcohol, nicotine, or cannabis engender addiction by changing the structure of brains, or does the structure of brains incline some people toward using those substances? In standard brain ...

For the first time, archaeologists have used advanced scientific techniques on 4,000-year-old dental plaque to confirm traces of betel nut chewing in ancient Thai communities. Betel nuts are usually ...

Chemical analysis of preserved human hair from a cave in Menorca revealed direct evidence of hallucinogenic drug use in Europe 3,000 years ago. Alkaloids from nightshade plants and ephedra show ...

Archaeologists working in the Tabuk province of Arabia have found the earliest documented evidence of the ritual application of a psychoactive substance, according to a new study published in ...

Use of antipsychotic and psychoactive drugs following surgery generally fell in various settings among those experiencing postoperative delirium, according to a study published in the Journal of the ...

Psychedelics, psychoactive substances that alter people's perceptions, mood and thought patterns, have recently shown promise ...

Archaeologists in Peru have discovered a 2,500-year-old secret drug room filled with hollowed-out bird bones containing traces of psychedelic snuff and tobacco. The presence of the "snuff tubes" in a ...