A research team of the University Medical Center Mainz has succeeded in observing for the first time how G protein-coupled receptors in living cells actually respond to activating substances. The ...

A bitter taste receptor, TAS2R14, has been shown to respond to both extracellular and intracellular signals. Indeed, it can respond to both signals simultaneously. This finding is especially ...

Partial opioid agonists have mixed or limited action when they bind to your opioid receptors. So, doctors often use them to treat opioid use disorder. Protein receptor sites are like keyholes on the ...

Many people are familiar with histamine, a biological molecule that serves as a key driver of allergic reactions and other immune responses. However, histamine is also a major neurotransmitter in the ...

Opioid antagonists help block opioid signaling in the central nervous system, and they include medications such as naloxone and naltrexone. Your central nervous system has many different receptors on ...

A new study reveals a critical vulnerability in a brain receptor targeted by a rare autoimmune disease. Researchers have ...