The discovery of ribosomes dates back to the 1950s, when George Palade first observed dense particles in the cytoplasm of cells using electron microscopy. These particles were later named "ribosomes" ...

One year later, in these Hot Papers, Ramakrishnan's group described the complete structure of the 30S subunit at 3 Angstrom resolution, both isolated and complexed with antibiotics. This information ...

Evidence of human construction work is all around us: on the roads we travel, in the buildings we occupy and now even in outer space. But one form of “human construction” quietly does its job without ...

At the end of the 1970s, Ada Yonath decided she was going to generate crystal structures of the ribosome using x-ray crystallography to establish the exact location of every atom -- considered an ...

This image highlights two alternatives for the ribosome to be recruited to an mRNA that is still being synthesized by RNA polymerase (RNAP). RNAP (left, red) can directly deliver the mRNA to the entry ...

Members of NAI’s team at Georgia Tech have a new paper in Molecular Biology and Evolution describing an analysis of ribosomal structure and sequence. Their approach chronicles the ribosome’s evolution ...