Sirtuin genes and the proteins they encode were already linked to longevity in yeast. Now, a previously overlooked member of the family has excited researchers who study aging At last, a member of the ...

Jellyfish, sea sponges, amoebas and other animals on the early branches of the tree of life defy conventional aging. A new study reveals diversity of proteins called sirtuins in these animals compared ...

A study has described a mechanism that plays a key role in the evolution of Alzheimer’s disease. According to the paper, the activation of the protein Sirtuin 1 in a murine model with familial ...

A new research paper titled "Sirtuin 6 activation rescues the age-related decline in DNA damage repair in primary human chondrocytes" has been published in Aging. While advanced age is widely ...

A formerly underappreciated member of the sirtuin family of proteins may hold the key to youthfulness and is the first sirtuin shown to specifically govern the activity of genes, scientists report.

Mammals convert the energy stored in adipose (fat) tissue into heat via a process known as thermogenesis. This process is regulated by a family of signaling proteins called sirtuins. A recent study by ...

A potentially promising approach to treating Alzheimer’s disease has been developed by researchers studying sirtuin, a protein thought capable of extending lifespan in laboratory animals. Using mice ...

The potential protective effect of sirtuin enzymes in age-related diseases, including cardiovascular diseases, remains an area of intense investigation. Now, researchers has determined that sirtuin 1 ...

Animals on the early branches of the tree of life, such as jellyfish and sea sponges, defy the usual conventions of aging. Some show abilities to regenerate damaged or missing tissues, halt or reverse ...