Data demonstrating superior selectivity, safety and pharmacokinetics of RGT-0474060 were presented at the 21st Annual Huntington’s Disease ...
These random molecules were fed a collection of three-base-long RNAs, each linked to a chemical tag. The idea was that if a molecule is capable of ligating one of these short RNA fragments to itself, ...
Pharmaceutical Technology on MSN
RNA-targeting small molecules: A new frontier of drug discovery
With big pharma signalling interest in novel RNA-targeted approaches, the term “druggable” is being redefined as technology ...
Researchers at the MRC Laboratory of Molecular Biology in Cambridge have discovered a ribozyme that is shockingly small, yet ...
Emerging modalities such as self-amplifying and circular RNA, expanding oncology and rare-disease applications, and scalable manufacturing are creating high-growth investment avenues, supported by ...
With the question of immunotherapeutics’ efficacy answered in the resounding affirmative, the challenge has shifted to the practical considerations of how to cost-effectively manufacture these highly ...
Morning Overview on MSN
RNA strand that nearly self-replicates could unlock life’s origin
A 45-nucleotide strand of RNA can now synthesize both its mirror-image complement and a copy of itself, bringing scientists ...
One of the greatest mysteries of our planet is how a soup of lifeless chemicals transformed into the first living cell. There are several competing theories about where this happened, from frozen ...
RNA immunity is a defense system against viruses, including the cross-species regulation of exogenous miRNAs and the endogenous RNA-based immune system. Figure created with BioRender.com. Conventional ...
Thermo Fisher Scientific Introduces Sequential Protein/DNA/RNA Extraction Kit That Enables Genomic, Transcriptomic and Proteomic Analysis from a Single Sample to Support Cancer and Disease ...
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