Prostate cancer remains a global health challenge, ranking as the second most common malignancy among men. While early-stage disease can be effectively managed, advanced forms-particularly metastatic ...

Image Caption: The role of SOX2 in lineage conversion from CRPC to NEPC. SOX2’s role in treatment resistance is particularly significant. It supports resistance to chemotherapy by inducing a ...

Sox2 is a stem cell protein that’s known to proliferate after a spinal cord injury. Now researchers at UT Southwestern and Indiana University are proposing a method for harnessing the protein to ...

Disseminated tumor cells in the bone marrow of ductal carcinoma in situ patients. This is an ASCO Meeting Abstract from the 2011 ASCO Annual Meeting I. This abstract does not include a full text ...

miRNA profiling in resectable NSCLC by multiplex next-generation sequencing. This is an ASCO Meeting Abstract from the 2012 ASCO Annual Meeting I. This abstract does not include a full text component.

Researchers have found that heterozygous loss of the methyl-CpG binding protein Zbtb38 downregulated the expression of the transcription factors Nanog and Sox2, as well as genes involved in epiblast ...