A powerful editorial published today in Brain Medicine raises alarm about a previously overlooked threat to brain development and public health: the disruption of sterol biosynthesis by common ...

Triterpenoid saponins are key bioactive compounds responsible for the medicinal value of many plants, yet how plants regulate the balance between saponin production and sterol biosynthesis has ...

Triterpenoid saponins are widely valued for their diverse pharmacological activities and also play important defensive roles ...

Medication-induced disruption of sterol biosynthesis poses significant risks to brain development and function. At the top center of this schematic lies the cholesterol molecule—an anchor of ...

A breakthrough in understanding how a single-cell parasite makes ergosterol (its version of cholesterol) could lead to more effective drugs for human leishmaniasis, a parasitic disease that afflicts ...