Pulmonary surfactant is a mixture of phospholipids and proteins synthesized in alveolar type-II cells that is necessary for maintaining alveolar expansion at end-expiration. Phospholipids comprise ...
The lung provides an extensive surface area mediating gas exchange between epithelial cells and the capillaries in the alveolus. Since lung cells are in direct contact with environmental gases and ...
Surfactant replacement therapy for respiratory distress syndrome (RDS) in preterm infants is a major breakthrough in neonatal medicine. Prophylactic or very early surfactant administration in very ...
Preclinical studies suggest that exogenous surfactant may be of value in the treatment of the acute respiratory distress syndrome (ARDS), and two phase 2 clinical trials have shown a trend toward ...
In a recent study posted to the bioRxiv* preprint server, researchers discuss the role of a surfactant-mediated inflammatory response employed by human lungs against the severe acute respiratory ...
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