Like Goldilocks, the brain seeks proportions that are just right. The proper number of synapses or communication between nerve cells, determined early in life, is crucial to having a healthy brain ...
What causes synapses to wither in neurodegenerative diseases such as Alzheimer’s? Some researchers blame reactivation of microglia, which prune unneeded synapses during brain development. At the ...
Mutations in the RNA-binding protein fragile X mental retardation protein (FMRP) underlie the neuronal dysfunction observed in Fragile X syndrome (FXS). Gaining an understanding of the normal role of ...
In the central nervous system (CNS), the neurotrophins nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin 3 (NT3) and neurotrophin 4 (NT4) were initially characterized ...
Researchers recently discovered that an inhibitory brain receptor triggers synaptic pruning in adolescence. Drugs that selectively target these receptors, when administered during adolescence, can ...
Healthy adult brains are endowed with a vast number of synapses, structures that relay signals across nerve cells to enable communications, information processing and storage throughout the nervous ...
Healthy adult brains are endowed with a vast number of synapses, structures that relay signals across nerve cells to enable communications, information processing and storage throughout the nervous ...
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