Cancer cells have softer membranes than healthy cells. New nanoparticles exploit this physical difference to fuse selectively ...
As a fast and easy-to-use gene-editing technique, CRISPR is one of the biggest discoveries in 21 st century medical science, and an important facilitator of gene therapy development. Several gene ...
Explore RNA interference methods, comparing siRNA and shRNA for gene knockdown, their mechanisms, advantages, and ...
One person's side effect could be another person's treatment if we expand our perspective on small molecule drug targets, according to a new study published November 5, 2025, in npj Precision Oncology ...
Researchers introduce Variant-aware Cas-OFFinder, a web-based tool that improves CRISPR off-target predictions by incorporating individual genetic differences. By reconstructing allele-specific ...
HER2-positive cancers overexpress the human epidermal growth factor receptor 2. When expressed at abnormally high levels, HER2 leads to uncontrolled cell growth and a more aggressive behavior than ...
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