Neonatal hypertrypsinaemia with normal sweat chloride detected during CF screening may be related to trypsin activation. We have looked for mutations of the cationic trypsinogen (PRSS1) and pancreatic ...
MELBOURNE, Australia--(BUSINESS WIRE)--Propanc Biopharma, Inc. (OTCQB: PPCB) (“Propanc” or the “Company”), a biopharmaceutical company developing novel cancer treatments for patients suffering from ...
The genetics of pancreatic disease recently became the focus of much scrutiny. The first pancreatitis susceptibility gene to be discovered was PRSS1 (protease, serine 1). Mutations in PRSS1, which ...
(HealthDay)—Patients with type 1 diabetes have significantly lower serum trypsinogen levels than those without type 1 diabetes, according to a study published online Jan. 23 in Diabetes Care. Xia Li, ...
In this prospective multicentre study, a urinary trypsinogen-2 dipstick test was given to 412 patients presenting to the emergency room or hospitalized with acute abdominal pain. Sensitivity and ...
To survive tough times, cells sometimes resort to a form of self-cannibalism called autophagy. But autophagy can have a down side, destroying the pancreas by prematurely activating a digestive enzyme.