Throughout our lives, our bones are continuously remodeled to maintain strength, repair injuries and adapt to new stresses. Bone dynamics depend on two associated cell types: osteoblasts, which are ...

The discovery of a family with sequence similarity 102 member A (Fam102a) protein as a novel bone remodeling factor that regulates both osteoclast and osteoblast differentiation can aid the ...

Explore the vital role of bone marrow stem cells. Learn how they drive bone remodeling, immunity, and skeletal health in this complete guide.

It’s common to think of your bones as solid and unchanging, but they’re composed of living tissue constantly in flux. Consider: Every year, 15% of your spine and 5% of your hips are replaced with new ...

Drugs that selectively kill senescent cells may benefit otherwise healthy older women but are not a "one-size-fits-all" remedy, Mayo Clinic researchers have found. Specifically, these drugs may only ...

Osteocytes, the most abundant cells in bone tissue, have long been underestimated in their functional capacity. Traditionally viewed as passive entities, recent research has illuminated their pivotal ...

Fam102a-Rbpjl axis in osteoblast differentiation reveals significant insights into bone remodeling and may aid the development of therapeutic strategies. Bones are the living tissue on which the human ...