A rare inherited disorder, Xeroderma Pigmentosum (XP) is a photosensitive condition characterized by high susceptibility to skin cancers. XP follows the autosomal recessive pattern of inheritance.
Xeroderma pigmentosum, or XP, is a rare genetic disorder that prevents the skin from repairing sun damage. There are about 300 Americans currently living with XP, and the chances of being born in this ...
New insight into how xeroderma pigmentosum causative gene products ensure the accuracy of DNA repair
XPC protein acts as a sensor to detect various abnormalities in the DNA structure. The faithful repair of DNA is ensured by using the basal transcription factor TFIIH and XPA protein to verify the ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, No. 14 (Jul. 3, 2001), pp. 7817-7822 (6 pages) Sun exposure has been clearly implicated in premature skin ...
Bella Thorne’s latest movie, Midnight Sun, is aiming to draw awareness to a rare, real-life genetic condition where children grow up with an extreme sensitivity to sunlight. Bella’s character, 17-year ...
The following represents disclosure information provided by authors of this manuscript. All relationships are considered compensated. Relationships are self-held unless noted. I = Immediate Family ...
New insight into how xeroderma pigmentosum causative gene products ensure the accuracy of DNA repair
Our genomic DNA is continuously damaged by endogenous factors such as reactive oxygen species, and also by environmental factors such as ultraviolet light, radiation, and chemicals. Failure to repair ...
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