The protocol describes a method for capture of secreted hexahistidine-tagged proteins using expanded-bed adsorption immobilized-metal affinity chromatography. The starting material for the procedure ...

Oligonucleotides, the short strands of nucleic acids that are pivotal in genetic research and therapeutic applications, require precise analytical techniques for their characterization. Hydrophilic ...

IAM consists of a monolayer of phosphatidylcholine covalently bound to an inert silica support. A highly reproducible method to measure drug adsorption, IAM chromatography is inexpensive and fast in ...

Although biopharmaceutical manufacturing covers an extensive range, it is essential that each iteration of a unit operation is in compliance with an unyielding set of operational parameters and ...