Highly Sensitive Circulating Tumor DNA Assay Aids Clinical Management of Radiographically Occult Isolated Peritoneal Metastases in Patients With GI Cancer These cases highlight the challenges in ...
High-risk constitutional MLH1 methylation underlies a significant proportion of early-onset endometrial cancers and colorectal cancers with tumor MLH1 methylation. At the American Society of Clinical ...
Roughly one-half of all cases of Lynch syndrome with an identified gene mutation are associated with the MLH1 gene. (1) In addition to MLH1, scientists have identified four other gene alterations that ...
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