While off-label use may be permissible, contraindicated use still has a strong regulatory boundary as reinforced by FDA guidance finalized in 2025.

It is written: both systemic and topical corticosteroids can exacerbate or precipitate acne or even induce an acneform eruption. Corticosteroids are considered to be acnegenic comedogenic drugs, and ...

Boehringer Ingelheim is starting to inform physicians about a new contraindication for its oral anticoagulant drug Pradaxa (dabigatran). The company has told investigators in trials utilizing ...

Multicenter Randomized Trial of Centralized Nurse-Led Telephone-Based Care Coordination to Improve Outcomes After Surgical Resection for Colorectal Cancer: The CONNECT Intervention Drugs are approved ...

This chart represents information on select drugs that are contraindicated in women who are pregnant. Drugs that are contraindicated at a certain phase of pregnancy are noted.

The risks of benzodiazepine use for PTSD outweigh the benefits, per study results. Benzodiazepines worsened outcomes for patients with PTSD following various types of trauma. The risks outweigh the ...