Mutations in a gene linked to Crohn's disease deprive vital immune cells of their capacity to change modes, which leads to overreaction and inflammation, a recent study has found, per ScienceAlert.

A new study shows type I interferon fine-tunes macrophage mitochondria through the protein ISG15, boosting dead-cell ...

When our body fights an infection, the immune system must quickly activate defenses and trigger a beneficial inflammatory ...

Researchers have identified an enzyme that controls the maturation and long-term survival of tissue-resident macrophages.

UVA researcher Blandine Baffert, working in the lab of UVA Health’s Sanja Arandjelovic and collaborating with researchers in ...

Study findings map out a new way in which antiviral signals engage with cellular metabolism to balance defense and repair.

An increase in high-fat, high-fructose foods in people's diets has contributed to a dramatic increase in type 2 diabetes. This, in turn, has led to an increase in peripheral neuropathy—nerve damage, ...

Scientists at Mount Sinai have unveiled a bold new way to fight metastatic cancer by turning the tumor’s own defenses against ...

Trojan horse” approach may enable ‘antigen-independent’ therapy with potential to treat cancers not traditionally amenable to immunotherapy.