A protein once thought to simply help cancer cells avoid death turns out to do much more. MCL1 actively drives cancer ...

Researchers have just revealed that a protein called MCL1, already known to help cancer cells avoid death, also orchestrates ...

Two experimental drug approaches that target vulnerabilities in cancer cell metabolism may extend survival and enhance the effectiveness of standard chemotherapies for a highly aggressive type of ...

Sepsis, one of the most acute and serious disease complications in the intensive care unit, is caused by various infections and results in life-threatening organ dysfunction. The intestinal barrier ...

An impressive new study from a team of Australian researchers has identified the novel mechanism behind immune exhaustion. The findings point to a treatment method that could improve the success of ...

A sequential doublet chemotherapy regimen in patients (pts) with advanced endometrial adenocarcinoma (EC) and gynecological mixed müllerian tumors (MMT). Maintaining activity with tolerability? No ...

CD8+ T cells responding to persistent antigenic stimulation, for example during chronic viral infections and cancer, undergo a process named T-cell exhaustion. Exhausted T cells are heterogeneous, ...