If extrapyramidal symptoms (EPS) should occur, which of the fol... | Filo
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If extrapyramidal symptoms (EPS) should occur, which of the fol... | Filo
If extrapyramidal symptoms (EPS) should occur, which of the fol... | Filo
5 months ago
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Classify Rx on Instagram: "📍 Blood-Brain Barrier Penetration Domperidone = minimal BBB crossing → lower CNS side effects (less EPS, sedation, drowsiness). Metoclopramide = readily crosses BBB → higher risk of extrapyramidal symptoms (dystonia, akathisia, tardive dyskinesia). 📍 Extrapyramidal Risk Trade-off Metoclopramide’s central D2 antagonism causes acute dystonia, parkinsonism, and irreversible tardive dyskinesia (especially elderly, prolonged use). Domperidone’s peripheral action spares pa
0:09
Classify Rx on Instagram: "📍 Blood-Brain Barrier Penetration Domperidone = minimal BBB crossing → lower CNS side effects (less EPS, sedation, drowsiness). Metoclopramide = readily crosses BBB → higher risk of extrapyramidal symptoms (dystonia, akathisia, tardive dyskinesia). 📍 Extrapyramidal Risk Trade-off Metoclopramide’s central D2 antagonism causes acute dystonia, parkinsonism, and irreversible tardive dyskinesia (especially elderly, prolonged use). Domperidone’s peripheral action spares pa
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